162 / 172
162
management of rheumatoid arthritis: randomised double-
blind comparison. Lancet 1999;354:2106-11.
141.Katchamart W, Johnson S, Lin HJ, Phumethum V, Salliot
C, Bombardier C. Predictors for remission in rheumatoid
arthritis patients: A systematic review. Arthritis Care Res
(Hoboken) 2010;62:1128-43.
142.Fiehn C, Jacki S, Heilig B, Lampe M, Wiesmüller G, Richter
C, et al. Eight versus 16-week re-evaluation period in
rheumatoid arthritis patients treated with leflunomide or
methotrexate accompanied by moderate dose prednisone.
Rheumatol Int 2007;27:975-9.
143. Osiri M, Shea B, Robinson V, Suarez-Almazor M, Strand
V, Tugwell P, et al. Leflunomide for the treatment of
rheumatoid arthritis: a systematic review and metaanalysis. J
Rheumatol 2003;30:1182-90.
144. Reece RJ, Kraan MC, Radjenovic A, Veale DJ, O'Connor
PJ, Ridgway JP, et al. Comparative assessment of leflunomide
and methotrexate for the treatment of rheumatoid arthritis, by
dynamic enhanced magnetic resonance imaging. Arthritis
Rheum 2002;46:366-72.
145. Cohen S, Cannon GW, Schiff M, Weaver A, Fox R, Olsen
N, et al. Two-year, blinded, randomized, controlled trial of
treatment of active rheumatoid arthritis with leflunomide
compared with methotrexate. Utilization of Leflunomide in the
Treatment of Rheumatoid Arthritis Trial Investigator Group.
Arthritis Rheum 2001;44:1984-92.
146.Emery P, Breedveld FC, Lemmel EM, Kaltwasser JP,
Dawes PT, Gömör B, et al. A comparison of the efficacy and
safety of leflunomide and methotrexate for the treatment of
rheumatoid arthritis. Rheumatology (Oxford) 2000;39:655-65.
147.Sharp JT, Strand V, Leung H, Hurley F, Loew-Friedrich I.
Treatment with leflunomide slows radiographic progression of
rheumatoid arthritis: results from three randomized controlled
trials of leflunomide in patients with active rheumatoid