73 / 89
73
AND genetics) OR (Genetic Counseling OR
Inheritance pattern AND genetics) OR (Medical
Genetics OR genotype OR genetics[Subheading]
AND genetics) OR (DNA Mutational Analysis OR
Laboratory techniques and procedures OR Genetic
Markers OR diagnosis OR testing OR test OR
screening OR mutagenicity tests OR genetic
techniques OR molecular diagnostic techniques
AND genetics)) OR Prognosis/narrow)
Pico 3: Como determinar o prognóstico do paciente
(escore)?
Multiple Myeloma AND (staging OR system OR
stage OR stratification OR Durie-Salmon OR
International Staging System OR ISS OR neoplasm
staging OR score) AND prognosis
Pico4: Como definir os pacientes que deverão ser
tratados?
((Multiple
myeloma)
AND
(Monoclonal
gammopathy of undetermined significance OR
MGUS OR smoldering OR placebo OR observation
OR asymptomatic OR symptomatic)) OR ((Multiple
myeloma OR Monoclonal gammopathy of
undetermined significance OR MGUS OR
smoldering) AND (placebo OR observation OR
asymptomatic OR symptomatic) AND (comparative
study OR comparative studies OR epidemiologic
methods
OR
Therapy/Broad[filter]
OR
Prognosis/Broad[filter])