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4
Descrição do método de coleta de evidência:
Foram revisados artigos nas bases de dados do
MEDLINE (PubMed) e outras fontes de pesquisa,
sem limite de tempo. A estratégia de busca utilizada
baseou-se em perguntas estruturadas na forma
P.I.C.O. (das iniciais “Paciente”, “Intervenção”,
“Controle”, “
Outcome
”). Foram utilizados como
descritores:
Neuromyelitis
Optica,
Myelitis,
Transverse; Optic Neuritis, Devic’s syndrome, Devic
Disease, Visual Acuity, Vision Test Mutiple
Sclerosis,
diagnosis
differential,
Recurrence,
prevention & control, Disease-Free Survival;
Biological
Markers,
Autoantibodies,
Immunoglobulin G, Aquaporin 4, Aquaporins,
AQP4 protein, human; Multiprotein Complexes,
Signs and Symptoms, physiopathology, Severity of
Illness Index, therapeutic use, drug therapy,
Administration,
Oral;
Infusion
Intravenous,
Administration
&
dosage*,
Steroids,
Glucocorticoids,
Adrenal Cortex Hormones,
Adrenocorticotropic Hormone (ACTH), Anti-
Inflammatory Agents, Prednisone, Prednisolone,
Methylprednisolone,
Pulse
Therapy,
Drug;
Immunoglobulins, Intravenous; Immunossupressive
Agents; Immunosuppression, Immunotherapy,
Immunologic Factors, interferon, interferon-beta,
recombinant proteins, Blood Component Removal*,
Plasmapheresis OR Plasma Exchange OR double